Comparison of next-generation portable pollution monitors to measure exposure to PM2.5 from household air pollution in Puno, Peru.

ssessment of personal exposure to PM2.5 is critical for understanding intervention effectiveness and exposure-response relationships in household air pollution studies. In this pilot study, we compared PM2.5 concentrations obtained from two next-generation personal exposure monitors (the Enhanced Children MicroPEM or ECM; and the Ultrasonic Personal Air Sampler or UPAS) to those obtained with a traditional Triplex Cyclone and SKC Air Pump (a gravimetric cyclone/pump sampler). We co-located cyclone/pumps with an ECM and UPAS to obtain 24-hour kitchen concentrations and personal exposure measurements. We measured Spearmen correlations and evaluated agreement using the Bland-Altman method. We obtained 215 filters from 72 ECM and 71 UPAS co-locations. Overall, the ECM and the UPAS had similar correlation (ECM ρ = 0.91 vs UPAS ρ = 0.88) and agreement (ECM mean difference of 121.7 µg/m3 vs UPAS mean difference of 93.9 µg/m3) with overlapping confidence intervals when compared against the cyclone/pump. When adjusted for the limit of detection, agreement between the devices and the cyclone/pump was also similar for all samples (ECM mean difference of 68.8 µg/m3 vs UPAS mean difference of 65.4 µg/m3) and personal exposure samples (ECM mean difference of −3.8 µg/m3 vs UPAS mean difference of −12.9 µg/m3). Both the ECM and UPAS produced comparable measurements when compared against a cyclone/pump setup.

Challenges in the diagnosis of paediatric pneumonia in intervention field trials: recommendations from a pneumonia field trial working group.

Goodman D, Crocker ME, Pervaiz F, McCollum ED, Steenland K, Simkovich SM, Miele CH, Hammitt LL, Herrera P, Zar HJ, Campbell H, Lanata CF, McCracken JP, Thompson LM, Rosa G, Kirby MA, Garg S, Thangavel G, Thanasekaraan V, Balakrishnan K, King C, Clasen T, Checkley W, HAPIN Investigators

Global Infectious Disease Threats

The effect of a single 4CMenB vaccine booster in young people more than ten years after infant immunisation: protocol of an exploratory immunogenicity study.

Davis K, Ford K, Craik R, Galal U, Rollier CS, Pollard AJ

Maternal, Newborn + Child Health Young People's Health

Deep clinical and biological phenotyping of the preterm birth and small for gestational age syndromes: The INTERBIO-21 st Newborn Case-Control Study protocol.

Kennedy SH, Victora CG, Craik R, Ash S, Barros FC, Barsosio HC, Berkley JA, Carvalho M, Fernandes M, Cheikh Ismail L, Lambert A, Lindgren CM, McGready R, Munim S, Nellåker C, Noble JA, Norris SA, Nosten F, Ohuma EO, Papageorghiou AT, Stein A, Stones W, Tshivuila-Matala COO, Staines Urias E, Vatish M, Wulff K, Zainab G, Zondervan KT, Uauy R, Bhutta ZA, Villar J

Maternal, Newborn + Child Health

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.

Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepúlveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN, Abathina A, Abubakar I, Achidi E, Agbenyega T, Aiyegbo M, Akoto A, Allen A, Allen S, Amenga-Etego L, Amodu F, Amodu O, Anchang-Kimbi J, Ansah N, Ansah P, Ansong D, Antwi S, Anyorigiya T, Apinjoh T, Asafo-Agyei E, Asoala V, Atuguba F, Auburn S, Bah A, Bamba K, Bancone G, Barnwell D, Barry A, Bauni E, Besingi R, Bojang K, Bougouma E, Bull S, Busby G, Camara A, Camara L, Campino S, Carter R, Carucci D, Casals-Pascual C, Ceesay N, Ceesay P, Chau T, Chuong L, Clark T, Cole-Ceesay R, Conway D, Cook K, Cook O, Cornelius V, Corran P, Correa S, Cox S, Craik R, Danso B, Davis T, Day N, Deloukas P, Dembele A, deVries J, Dewasurendra R, Diakite M, Diarra E, Dibba Y, Diss A, Djimdé A, Dolo A, Doumbo O, Doyle A, Drakeley C, Drury E, Duffy P, Dunstan S, Ebonyi A, Elhassan A, Elhassan I, Elzein A, Enimil A, Esangbedo P, Evans J, Evans J, Farrar J, Fernando D, Fitzpatrick K, Fullah J, Garcia J, Ghansah A, Gottleib M, Green A, Hart L, Hennsman M, Hien T, Hieu N, Hilton E, Hodgson A, Horstmann R, Hughes C, Hussein A, Hutton R, Ibrahim M, Ishengoma D, Jaiteh J, Jallow M, Jallow M, Jasseh K, Jobarteh A, Johnson K, Joseph S, Jyothi D, Kachala D, Kamuya D, Kanyi H, Karunajeewa H, Karunaweera N, Keita M, Kerasidou A, Khan A, Kivinen K, Kokwaro G, Konate A, Konate S, Koram K, Kwiatkowski D, Laman M, Le S, Leffler E

Malaria Maternal, Newborn + Child Health

International estimated fetal weight standards of the INTERGROWTH-21st Project.

Stirnemann J, Villar J, Salomon LJ, Ohuma E, Ruyan P, Altman DG, Nosten F, Craik R, Munim S, Cheikh Ismail L, Barros FC, Lambert A, Norris S, Carvalho M, Jaffer YA, Noble JA, Bertino E, Gravett MG, Purwar M, Victora CG, Uauy R, Bhutta Z, Kennedy S, Papageorghiou AT

Maternal, Newborn + Child Health