The Asymmetric Cell Division Regulators Par3, Scribble and Pins/Gpsm2 Are Not Essential for Erythroid Development or Enucleation.
Wölwer CB, Gödde N, Pase LB, Elsum IA, Lim KY, Sacirbegovic F, Walkley CR, Ellis S, Ohno S, Matsuzaki F, Russell SM, Humbert PO
Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.
Elsum IA, Yates LL, Pearson HB, Phesse TJ, Long F, O'Donoghue R, Ernst M, Cullinane C, Humbert PO
Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation.
Elsum IA, Martin C, Humbert PO
The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man.
Elsum I, Yates L, Humbert PO, Richardson HE
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.
Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO