In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface.
Davis C, Harris HJ, Hu K, Drummer HE, McKeating JA, Mullins JG, Balfe P
Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2.
Boo I, teWierik K, Douam F, Lavillette D, Poumbourios P, Drummer HE
Hepatitis C virus nonstructural protein 5B is involved in virus morphogenesis.
Gouklani H, Bull RA, Beyer C, Coulibaly F, Gowans EJ, Drummer HE, Netter HJ, White PA, Haqshenas G
Role of conserved cysteine residues in hepatitis C virus glycoprotein e2 folding and function.
McCaffrey K, Boo I, Tewierek K, Edmunds ML, Poumbourios P, Drummer HE
Role for the terminal clasp of HIV-1 gp41 glycoprotein in the initiation of membrane fusion.
Lay CS, Ludlow LE, Stapleton D, Bellamy-McIntyre AK, Ramsland PA, Drummer HE, Poumbourios P
Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 contain reduced cysteine residues essential for virus entry.
Fraser J, Boo I, Poumbourios P, Drummer HE
Hepatitis C