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The association between latrine use and trachoma: a secondary cohort analysis from a randomized clinical trial.

Haile M, Tadesse Z, Gebreselassie S, Ayele B, Gebre T, Yu SN, Stoller NE, Gaynor BD, Porco TC, Emerson PM, Lietman TM, Keenan JD

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  • Journal The American journal of tropical medicine and hygiene

  • Published 03 Sep 2013

  • Volume 89

  • ISSUE 4

  • Pagination 717-20

  • DOI 10.4269/ajtmh.13-0299

Abstract

Latrine use has been promoted as a component of an integrated strategy for trachoma control. As part of a randomized trial in Ethiopia, 12 communities received a mass azithromycin distribution followed by a latrine promotion intervention. A random sample of children ages 0-9 years in each community was monitored longitudinally for ocular chlamydia. After latrine construction ended, those communities with a higher proportion of households using latrines were more likely to experience a reduction in the prevalence of ocular chlamydia. Specifically, for each 10% increase in latrine use, there was a 2.0% decrease (95% confidence interval = 0.2-3.9% decrease) in the community prevalence of ocular chlamydia over the subsequent year (P = 0.04).