close search

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.

Wang G, Drinkwater N, Drew DR, MacRaild CA, Chalmers DK, Mohanty B, Lim SS, Anders RF, Beeson JG, Thompson PE, McGowan S, Simpson JS, Norton RS, Scanlon MJ

VIEW FULL ARTICLE
  • Journal Journal of molecular biology

  • Published 14 Jul 2016

  • Volume 428

  • ISSUE 20

  • Pagination 3986-3998

  • DOI 10.1016/j.jmb.2016.07.001

Abstract

values of 2.1nM and 0.4nM, respectively. To our knowledge, this is the most potent strain-transcending peptide reported to date and represents a valuable tool to characterize the AMA1-RON2 interaction.